Technology Legacy

A technology foundation and legacy built through years of visual neuroprosthetics work

Cortigent’s work builds on years of experience developing implantable visual neuroprosthetics, including Argus II and the Orion Early Feasibility Study.

Technology timeline

From retinal stimulation to cortical neurostimulation

Foundational years

Second Sight Medical Products

Development of implantable visual neuroprosthetic systems, wireless communication and patient-fitting methods.

2011–2019

Argus II commercial experience

With more than 350 implants, Argus II was an FDA-approved retinal prosthesis marketed from 2011 to 2019. Although no longer commercially available, the experience gained through its development helped shape Cortigent’s current platform.

2017 onward

Orion Early Feasibility Study

The electrode array moved from the retina to the visual cortex to investigate artificial vision through precise cortical stimulation.

Cortigent today

One platform, two programs

Precision neurostimulation for artificial vision and recovery of upper-limb function following stroke.

Modern illustrative rendering of the historical Argus II retinal prosthesis configuration

Illustrative rendering of the historical Argus II implant configuration.

Legacy contribution

Experience informing the current platform

Device designImplantable systemsHardware, packaging, and reliability experience.
CommunicationWireless power and dataExternal and implanted components working together.
SoftwareStimulation strategiesMapping and patterned activation of electrodes.
ClinicalHuman-use experienceStudy operations, patient fitting, and long-term follow-up.

Historical video

Historical patient stories, presented in context

These Argus II patient stories illustrate the human impact of Cortigent’s historical visual-neuroprosthetics work. They do not depict Orion.

Historical context

Argus II was implanted in more than 350 patients and marketed from 2011 to 2019 and is no longer commercially available.

Historical video

German Argus II patient stories

German patients share their experiences with the Argus II retinal prosthesis.

Experience carried forward into today’s programs

Cortigent is applying this foundation to two current programs built on its cortical-surface platform.

Current Cortigent cortical implant assembly