Technology

Targeted electrical stimulation at the surface of the brain

Cortigent uses precisely and independently controlled micro-pulses of electricity to stimulate selected neuron bundles through an electrode array placed on the cortex (brain surface) rather than penetrating into brain tissue.

Where Cortigent fits

Precision neurostimulation within the broader brain-computer interface field

Brain-computer interfaces (BCIs) can read neural activity, deliver stimulation or combine both functions. Cortigent focuses on cortical-surface precision neurostimulation.

Broad field

Brain-Computer Interfaces

BCI systems may sense neural activity, deliver stimulation or combine multiple interface functions.

Neurosensing

Reading Neural Activity

Systems in the broader field may detect neural signals for communication or control of external devices.

Cortigent focus

Precision Neurostimulation

We are developing systems that deliver real-time dynamic stimulation control through an array placed on the cortex.

How the platform works

A coordinated implant, external processor and software system

Implanted and external components work together to convert program-specific inputs into precisely controlled patterns of cortical stimulation.

1

Define the input

Program-specific input guides stimulation of the visual cortex or the motor cortex.

2

Process the signal

External hardware and software convert information into a programmed stimulation pattern.

3

Communicate wirelessly

The system sends power and data to implanted electronics without a percutaneous connection.

4

Stimulate targeted cortex

A multi-electrode surface array delivers controlled micro-pulses to selected neuron clusters.

Cortical surface array

Designed to rest on the cortex rather than penetrate brain tissue

Because the array rests on the surface of the brain rather than penetrating into brain tissue, our approach is able to deliver precisely controlled electrical pulses to selected areas of neuron clusters.

Multi-electrode arraySixty independently controlled, electrode drivers enable targeted stimulation across selected cortical regions.

Software-controlled stimulationTiming, intensity, location, pattern and electrode combinations can be programmed for the development application.

Wireless architectureImplanted and external components work together without wires crossing the skin.

Illustration of Orion hardware and the cortical-surface connection

Illustrative technical view of the cortical-surface connection.

A connected implant, cortical array and external system

Orion system components
External system

Wearable input and processing

For Orion, the camera and processor translate visual information into stimulation patterns.

Implanted electronics and receiver coil
Implanted electronics

Power, communication and pulse generation

The receiver and implanted electronics deliver dynamic power, communication and programmed pulses to the cortical array.

Close view of the Cortigent electrode array
Cortical array

Precision stimulation at the brain surface

Sixty independent electrodes support patterned stimulation across selected regions of the brain’s surface.

Exploring more precise patterns through software

Dynamic current steering and virtual-electrode research explores how software may create more precise stimulation patterns using the 60-electrode array.

Research context

These stimulation strategies are research concepts and may be evaluated separately from an FDA-authorized clinical protocol.

Two schematic electrode grids highlighting different groups to illustrate programmed stimulation patterns

Conceptual illustration of stimulation patterns.

Platform applications

Two current programs with room for future research

Orion and the Stroke Recovery System are Cortigent’s current development programs. The platform is expected to support additional areas of research as our technology advances.

Visual cortex

Orion® Visual Cortical Prosthesis System

Program-specific camera processing and visual cortex stimulation.

Explore Orion

Motor cortex

Stroke Recovery System

Program-specific stimulation intended for investigation alongside rehabilitation.

Explore Stroke Recovery